Protein Details: Potassium voltage-gated channel subfamily A member 2

Protein ID

ICDB_Pro_0413

Protein Name

Potassium voltage-gated channel subfamily A member 2

Gene Name

kcna2

Organism

Xenopus laevis (African clawed frog)

Length

499 amino acids

AlphaFoldDB

AF-P22739-F1-model_v4.pdb

Function

Sequence

MTVATGDLTDGSVGFAGHPQDSYDPEPDHECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYFYQSGGRLRRPVNVPLDIFSEEIRFYELGEEAMEIFREDEGFIKEEERPLPDNEFQKQVWLLFEYPESSGPARIIAIISVTVILISIVSFCLETLPVFRDENEDMHGSGGNYYSYPNSTVRFQKSNTFTDPFFIVETLCIIWFSFEFLVRFLACPSKAVFFTNLMNIIDIVAIIPYFITLGTELAEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLNASMRELGLLIFFLFIGVILFSSAVFFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLQKSRSASTLSKSDYMEIQEGVNHSNEDFREKNLKTANCTLGNTNYVNITKMLTDV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in tadpole brain and spinal cord.

DOI ID

10.1016/0896-6273(90)90223-3; 10.1038/ng.3239